Barcelona defender Samuel Umtiti, has confirmed that he has muscle problems.
The former Lyon player has suffered injury after being called with France national team, while Didier Deschamps replaced him with Eliaquim Mangalan.
Umtiti could return in action after three weeks, but his form is not expected to be adequate for El Clasico 3 December.
But Barcelona can can be happy with the return of Gerard Pique, who will be back after the national games.
Aleix Vidal, Jeremy Mathieu and Jordi Alba are also injured.